Neuroinflammation at the Gray–White Matter Interface in Active-Duty U.S. Special Operations Forces
Brian L. Edlow, Chieh-En J. Tseng, Natalie Gilmore, Isabella R. McKinney, Samantha L. Tromly, Katryna B. Deary, Collin G. Hu, Brian C. Healy, David S. Priemer, Christine L. Mac Donald, Kristen Dams-O’Connor, Douglas N. Greve, Yelena G. Bodien, Daniel P. Perl, Jacob M. Hooker, Nicole R. Zürcher · 2024
Read Neuroinflammation at the Gray–White Matter Interface in Active-Duty U.S. Special Operations Forces by Brian L. Edlow, Chieh-En J. Tseng, Natalie Gilmore, Isabella R. McKinney, Samantha L. Tromly, Katryna B. Deary, Collin G. Hu, Brian C. Healy, David S. Priemer, Christine L. Mac Donald, Kristen Dams-O’Connor, Douglas N. Greve, Yelena G. Bodien, Daniel P. Perl, Jacob M. Hooker, Nicole R. Zürcher (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11685501.txt.
Description
Autopsy studies of military personnel exposed to repeated blasts show scarring where gray and white matter meet in the brain, but no scan can yet detect that damage in life. Edlow and co-authors test whether PET imaging of inflammation can fill the gap.
The team scanned 27 active-duty Special Operations personnel with high blast exposure, using a tracer that marks inflamed tissue. Five of them, about 19 percent, showed signal at the gray-white interface more than two standard deviations above the mean of nine healthy civilian controls. Blast exposure totals did not differ between the five and the rest. The authors stress the link between inflammation and scarring is unproven, but the scans give a starting point for a biomarker.
Catalog record
| CREATOR | Brian L. Edlow, Chieh-En J. Tseng, Natalie Gilmore, Isabella R. McKinney, Samantha L. Tromly, Katryna B. Deary, Collin G. Hu, Brian C. Healy, David S. Priemer, Christine L. Mac Donald, Kristen Dams-O’Connor, Douglas N. Greve, Yelena G. Bodien, Daniel P. Perl, Jacob M. Hooker, Nicole R. Zürcher |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 20 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |