Enhanced glucose production in norepinephrine and palmitate stimulated hepatocytes following endurance training
Ken D. Sumida, Vera M. Lordan, Casey M. Donovan · 2024
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Description
Ken Sumida, Vera Lordan, and Casey Donovan present a 2024 rat study on how training changes liver sugar output. During long exercise, the liver makes new sugar once stores run low. Trained livers make more, above all when a stress hormone calls. Past work mixed that hormone with others. This study isolates its effect on liver cells from trained and untrained rats.
Even with no hormone, trained cells made far more sugar. At every hormone dose, trained cells stayed ahead. Their hormone-driven boost was also larger, about 36 percent against 19. Lactate intake rose in step and fully covered the extra sugar made. A fatty acid also lifted output in trained cells. Training tunes the liver itself, the authors conclude.
Catalog record
| CREATOR | Ken D. Sumida, Vera M. Lordan, Casey M. Donovan |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 33 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |