A comprehensive benchmark study of methods for identifying significantly perturbed subnetworks in cancer

Le Yang, Runpu Chen, Steve Goodison, Yijun Sun · 2024

Read A comprehensive benchmark study of methods for identifying significantly perturbed subnetworks in cancer by Le Yang, Runpu Chen, Steve Goodison, Yijun Sun (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11684898.txt.

Description

Network-based methods utilize protein–protein interaction information to identify significantly perturbed subnetworks in cancer and to propose key molecular pathways. Numerous methods have been developed, but to date, a rigorous benchmark analysis to compare the performance of existing approaches is lacking.

Catalog record

CREATORLe Yang, Runpu Chen, Steve Goodison, Yijun Sun
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE47 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11684898

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