Cyto-Safe: A Machine Learning Tool for Early Identification of Cytotoxic Compounds in Drug Discovery
Francisco · 2024
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Description
Feitosa and co-authors built a free web tool that flags chemicals likely to harm cells, aiding early drug hunts. Drug teams want to drop toxic compounds fast, before costly tests or animal use. Their 2024 paper presents Cyto-Safe, a tool trained on about ninety thousand compounds. Each compound was tested against two cell lines, one mouse and one human.
Users can type a chemical code, upload a file, or sketch a molecule by hand. The tool answers with a toxic or safe call for each cell line, a confidence score, and an explanation view. Machine learning models read the structure to make the call. The team offers the app in public at no cost.
Catalog record
| CREATOR | Francisco |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |