Bidirectional Modulation on Electroporation Induced by Membrane Tension Under the Electric Field
Ping Ye, Lulu Huang, Kuiwen Zhao · 2024
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Description
Ping Ye, Lulu Huang, and Kuiwen Zhao study how the angle of an electric field changes pore opening in cell walls in a 2024 paper. The work bears on a cancer treatment that uses electric pulses to kill tumor cells without heat. Tumor cells come in many shapes, so the field meets each cell wall at a different angle.
Using computer models of the cell wall, the team varied the field angle and tracked wall tension and pore growth. Low angles eased tension and helped pores form, while high angles raised tension and blocked pores. Water also slipped into the wall early and tilted the pores. The results point to field angle as a lever teams can tune to make treatment work better.
Catalog record
| CREATOR | Ping Ye, Lulu Huang, Kuiwen Zhao |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |