Risk factors and protective measures for desmoid tumours in familial adenomatous polyposis: retrospective cohort study
Emanuele Rausa, Valeria Duroni, Davide Ferrari, Stefano Signoroni, Chiara M Ciniselli, Sara Lauricella, Clorinda Brignola, Maria T Ricci, Alessandro Gronchi, Paolo Verderio, Marco Vitellaro · 2024
Read Risk factors and protective measures for desmoid tumours in familial adenomatous polyposis: retrospective cohort study by Emanuele Rausa, Valeria Duroni, Davide Ferrari, Stefano Signoroni, Chiara M Ciniselli, Sara Lauricella, Clorinda Brignola, Maria T Ricci, Alessandro Gronchi, Paolo Verderio, Marco Vitellaro (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11683362.txt.
Description
Emanuele Rausa and co-authors review two decades of registry data to learn what raises the risk of desmoid tumors in people with familial adenomatous polyposis, in a 2024 study. The inherited condition floods the colon with polyps, and after colon surgery, these slow but relentless tumors become a leading worry. Of 202 operated patients, 21 developed abdominal desmoids.
Surgery type mattered. An open approach more than doubled risk versus keyhole surgery, and removing the rectum too tripled it versus sparing it. A family history of desmoids nearly tripled risk as well. Cancer found at surgery, oddly, came with lower risk. Nine in ten patients stayed desmoid-free over a median 84 months. The authors back gentler surgery and dedicated tumor surveillance.
Catalog record
| CREATOR | Emanuele Rausa, Valeria Duroni, Davide Ferrari, Stefano Signoroni, Chiara M Ciniselli, Sara Lauricella, Clorinda Brignola, Maria T Ricci, Alessandro Gronchi, Paolo Verderio, Marco Vitellaro |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 24 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |