Antiviral activity of Ferula assa-feotida on HSV-1, 2 in vitro
Javad Charostad, Tahere Navidfar, Masoumeh Kiani, Paul Schinitzler, Akram Astani · 2024
Read Antiviral activity of Ferula assa-feotida on HSV-1, 2 in vitro by Javad Charostad, Tahere Navidfar, Masoumeh Kiani, Paul Schinitzler, Akram Astani (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11682560.txt.
Description
Javad Charostad and co-authors present a 2024 lab study of a plant resin against the herpes simplex viruses. Ferula assa-feotida, a pungent traditional remedy, was tested on HSV-1 and HSV-2 growing in monkey kidney cells. The standard drug acyclovir served as the yardstick.
The resin blocked half the viral plaques at very low concentrations for both virus types. Timing mattered most. When the virus was soaked in the extract before meeting the cells, infectivity fell by over ninety-five percent for HSV-1 and about eighty-nine percent for HSV-2. Treating cells before or after infection did nothing detectable. The pattern points to a direct attack on the virus early in its cycle. The authors propose the extract as a candidate antiviral lead.
Catalog record
| CREATOR | Javad Charostad, Tahere Navidfar, Masoumeh Kiani, Paul Schinitzler, Akram Astani |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 15 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |