Onset and long-term duration of immunity provided by a single vaccination with recombinant a Marek’s disease virus with REV-LTR insertion
Jun Dai, Cuiping Song, Lei Tan, Yingjie Sun, Ning Tang, Yang Qu, Ying Liao, Xusheng Qiu, Chan Ding · 2024
Read Onset and long-term duration of immunity provided by a single vaccination with recombinant a Marek’s disease virus with REV-LTR insertion by Jun Dai, Cuiping Song, Lei Tan, Yingjie Sun, Ning Tang, Yang Qu, Ying Liao, Xusheng Qiu, Chan Ding (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11681624.txt.
Description
Jun Dai and co-authors test how fast and how long a single vaccine shot guards chickens against Marek's disease, a contagious tumor-causing virus of poultry. Their vaccine candidate is a rebuilt virus carrying an inserted gene segment, already shown to weaken the disease strain. Their 2024 study vaccinates day-old chicks, then challenges them with a fierce field strain at set times.
Protection began by day three after the shot and was good by day five. Challenged groups were checked for symptoms and weight gain. Immunity lasted at least one hundred eighty days, the full span tested. Counting the natural resistance older birds gain, the authors argue the shot likely protects for life. The results guide how such a vaccine would be used on farms.
Catalog record
| CREATOR | Jun Dai, Cuiping Song, Lei Tan, Yingjie Sun, Ning Tang, Yang Qu, Ying Liao, Xusheng Qiu, Chan Ding |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |