Determinants of Leptomeningeal Collateral Status in Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis of Observational Studies
Kunyi Li, Hua Jiang, Jianping Yu, Yong Liu, Lili Zhang, Bi Ma, Shu Zhu, Yinkuang Qi, Shuang Li, Yan Huang, Yuhan Yang, Xun Xia, Lan Wen · 2024
Read Determinants of Leptomeningeal Collateral Status in Acute Ischemic Stroke: A Systematic Review and Meta‐Analysis of Observational Studies by Kunyi Li, Hua Jiang, Jianping Yu, Yong Liu, Lili Zhang, Bi Ma, Shu Zhu, Yinkuang Qi, Shuang Li, Yan Huang, Yuhan Yang, Xun Xia, Lan Wen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11681590.txt.
Description
Kunyi Li and a large team pool studies on backup blood flow in acute stroke, in this 2024 systematic review and meta-analysis. When a brain artery blocks, leptomeningeal collaterals can route blood around the blockage, and their strength strongly shapes outcomes. What determines collateral strength was unclear.
More than eighty studies with over seventeen thousand patients met the criteria, and thirty-one candidate factors were analyzed. Worse collateral status tracked with older age, male sex, hypertension, diabetes, atrial fibrillation, cardioembolic stroke, internal carotid blockage and higher admission blood sugar. The authors note that hypertension and diabetes are modifiable, making them levers for protecting collateral flow before stroke strikes.
Catalog record
| CREATOR | Kunyi Li, Hua Jiang, Jianping Yu, Yong Liu, Lili Zhang, Bi Ma, Shu Zhu, Yinkuang Qi, Shuang Li, Yan Huang, Yuhan Yang, Xun Xia, Lan Wen |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |