Advancements in Nanoparticle-Based Adjuvants for Enhanced Tuberculosis Vaccination: A Review
Jiao Wang, Zian Zhao, Quan Wang, Jingyu Shi, Duo Wai-Chi Wong, James Chung-Wai Cheung · 2024
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Description
Jiao Wang and five co-authors review in 2024 how tiny particles could sharpen tuberculosis vaccines. Tuberculosis still kills on a vast scale, and the century-old vaccine protects unevenly, so better boosters, called adjuvants, are in demand.
Nanoparticle adjuvants carry the vaccine's key fragments in spheres that immune cells swallow eagerly, releasing their cargo slowly for a longer, stronger response. The review tours the main particle families and the physical traits that make each work, from size to surface charge. It weighs gains in delivery, safety, and immune strength, a design brief for the next generation of TB shots.
Catalog record
| CREATOR | Jiao Wang, Zian Zhao, Quan Wang, Jingyu Shi, Duo Wai-Chi Wong, James Chung-Wai Cheung |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 54 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |