Expression of GnRH, Kisspeptin, and Their Specific Receptors in the Ovary and Uterus in Deslorelin-Treated Late-Prepubertal Bitches †
Muhammet Ali Karadağ, Aykut Gram, Sabine Schäfer-Somi, Selim Aslan, Duygu Kaya, Junwei Li, Dong Zhou, Shiqiang Ju · 2024
Read Expression of GnRH, Kisspeptin, and Their Specific Receptors in the Ovary and Uterus in Deslorelin-Treated Late-Prepubertal Bitches † by Muhammet Ali Karadağ, Aykut Gram, Sabine Schäfer-Somi, Selim Aslan, Duygu Kaya, Junwei Li, Dong Zhou, Shiqiang Ju (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11680279.txt.
Description
Karadağ and co-authors study how a hormone implant used to delay puberty in dogs changes reproductive signaling in the ovary and uterus. The implant releases deslorelin, and vets use it to postpone breeding. Two hormone systems, GnRH and kisspeptin, normally switch puberty on, so the team measured them after treatment.
Tissue from twenty-five young female dogs was compared across dogs that came into heat, dogs that did not, and untreated controls. Deslorelin lowered some gene signals, and the pattern differed between groups. The authors conclude the implant cannot be relied on to trigger a fertile heat in late-prepubertal dogs, while noting that larger studies are needed to settle the question.
Catalog record
| CREATOR | Muhammet Ali Karadağ, Aykut Gram, Sabine Schäfer-Somi, Selim Aslan, Duygu Kaya, Junwei Li, Dong Zhou, Shiqiang Ju |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |