Venom from Loxosceles Spiders Collected in Southeastern and Northeastern Brazilian Regions Cause Hemotoxic Effects on Human Blood Components
Rafaela Silva-Magalhães, Ayla Mel Gomes dos Santos, Ana Luiza Silva-Araújo, Pamella Luize Peres-Damásio, Valéria Gonçalves de Alvarenga, Luciana Souza de Oliveira, Eladio Flores Sanchez, Carlos Chávez-Olórtegui, Luana Silveira da Rocha Nowicki Varela, Ana Luiza Bittencourt Paiva, Clara Guerra-Duarte · 2024
Read Venom from Loxosceles Spiders Collected in Southeastern and Northeastern Brazilian Regions Cause Hemotoxic Effects on Human Blood Components by Rafaela Silva-Magalhães, Ayla Mel Gomes dos Santos, Ana Luiza Silva-Araújo, Pamella Luize Peres-Damásio, Valéria Gonçalves de Alvarenga, Luciana Souza de Oliveira, Eladio Flores Sanchez, Carlos Chávez-Olórtegui, Luana Silveira da Rocha Nowicki Varela, Ana Luiza Bittencourt Paiva, Clara Guerra-Duarte (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11680057.txt.
Description
Rafaela Silva-Magalhães and co-authors test how venom from three Brazilian recluse spider species affects human blood, in a 2024 study. Bites from these spiders can trigger anemia, low platelets, and runaway clotting, yet some species' venoms were barely studied. Venom was milked from spiders kept at a national institute.
In lab tests, all three venoms burst red blood cells in a dose-dependent way. One species blocked platelet clumping triggered by two standard agents, while the other two provoked clumping instead. The split behavior matters for predicting how a bite may unfold. The authors say mapping these blood effects is a step toward better treatment of severe bites.
Catalog record
| CREATOR | Rafaela Silva-Magalhães, Ayla Mel Gomes dos Santos, Ana Luiza Silva-Araújo, Pamella Luize Peres-Damásio, Valéria Gonçalves de Alvarenga, Luciana Souza de Oliveira, Eladio Flores Sanchez, Carlos Chávez-Olórtegui, Luana Silveira da Rocha Nowicki Varela, Ana Luiza Bittencourt Paiva, Clara Guerra-Duarte |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |