Using Serum Metabolomic Signatures to Investigate Effects of Acupuncture on Pain-Fatigue-Sleep Disturbance in Breast Cancer Survivors
Hongjin Li, Ardith Z Doorenbos, Yinglin Xia, Jun Sun, Hannah Choi, Richard E Harris, Shuang Gao, Katy Sullivan, Judith M Schlaeger, Daniel Oscar Cicero · 2024
Read Using Serum Metabolomic Signatures to Investigate Effects of Acupuncture on Pain-Fatigue-Sleep Disturbance in Breast Cancer Survivors by Hongjin Li, Ardith Z Doorenbos, Yinglin Xia, Jun Sun, Hannah Choi, Richard E Harris, Shuang Gao, Katy Sullivan, Judith M Schlaeger, Daniel Oscar Cicero (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11679957.txt.
Description
Hongjin Li and co-authors report a 2024 study of acupuncture in breast cancer survivors. Many survivors live with a cluster of pain, fatigue, and poor sleep. Acupuncture eases that cluster, but its mechanism is unclear. Forty-two survivors took part in a single-arm trial. They received ten acupuncture sessions over five weeks. Fasting blood samples and symptom surveys were taken before and after.
Untargeted metabolomics profiled the blood chemistry in depth. Mixed models linked chemical shifts to symptom gains while adjusting for repeated measures. A chemical signature of response could one day predict who benefits most. It could also reveal pathways the needles engage, from energy to inflammation. Integrative care gains credibility when its effects show in blood data. The single-arm design limits causal claims, and the authors' analysis stays within that limit.
Catalog record
| CREATOR | Hongjin Li, Ardith Z Doorenbos, Yinglin Xia, Jun Sun, Hannah Choi, Richard E Harris, Shuang Gao, Katy Sullivan, Judith M Schlaeger, Daniel Oscar Cicero |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |