From Psychoactivity to Antimicrobial Agents: Multifaceted Applications of Synthetic Cathinones and Catha edulis Extracts
Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira, Celia Andrés Juan, Eduardo Pérez-Lebeña · 2024
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Description
Celia María Curieses Andrés and four co-authors survey synthetic cathinones, stimulant drugs related to the khat plant, from two directions at once. Since the 2000s these compounds have spread through the illegal drug market as stand-ins for amphetamines and cocaine. Their many chemical forms make them hard to detect and regulate, and they are tied to poisoning, addiction, and death. The review covers their chemistry, how the body handles them, and their toxic effects.
The second direction is newer: cathinone and extracts of the khat plant can kill bacteria, including drug-resistant strains of common pathogens. That activity hints at a role in the fight against antibiotic resistance. The authors call the idea an exciting frontier for drug design, while warning that any medical use must be weighed against the strong psychoactive risks.
Catalog record
| CREATOR | Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira, Celia Andrés Juan, Eduardo Pérez-Lebeña |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 62 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |