Plasma microRNAs as Biomarkers for Predicting Radiotherapy Treatment-Induced Cardiotoxicity in Lung Cancer
Paulina Kazlauskaitė, Ieva Vaicekauskaitė, Jonas Venius, Rasa Sabaliauskaitė, Rita Steponavičienė · 2024
Read Plasma microRNAs as Biomarkers for Predicting Radiotherapy Treatment-Induced Cardiotoxicity in Lung Cancer by Paulina Kazlauskaitė, Ieva Vaicekauskaitė, Jonas Venius, Rasa Sabaliauskaitė, Rita Steponavičienė (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11679788.txt.
Description
Paulina Kazlauskaitė and co-authors hunt for blood signals of heart harm from lung cancer radiation in a 2024 study. Radiation treats lung cancer well but can injure the heart over time. Current prediction tools for that injury are weak, so early warning markers are wanted.
The pilot study measured six small RNA molecules in plasma from fourteen patient pairs, sampled before and after therapy. Five of the six fell after treatment, while one rose. In patients whose heart strain marker climbed after therapy, one RNA's levels differed clearly from those with normal values. A combined panel of four RNAs scored well at flagging cardiac risk, and adding the strain marker improved it further. The authors frame microRNAs as early sentinels worth larger tests.
Catalog record
| CREATOR | Paulina Kazlauskaitė, Ieva Vaicekauskaitė, Jonas Venius, Rasa Sabaliauskaitė, Rita Steponavičienė |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 27 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |