Light-Emitting Diode Array with Optical Linear Detector Enables High-Throughput Differential Single-Cell Dielectrophoretic Analysis
Emerich Kovacs, Behnam Arzang, Elham Salimi, Michael Butler, Greg E Bridges, Douglas J Thomson, Arunas Ramanavicius · 2024
Read Light-Emitting Diode Array with Optical Linear Detector Enables High-Throughput Differential Single-Cell Dielectrophoretic Analysis by Emerich Kovacs, Behnam Arzang, Elham Salimi, Michael Butler, Greg E Bridges, Douglas J Thomson, Arunas Ramanavicius (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11679556.txt.
Description
Emerich Kovacs and co-authors present a lens-free device that reads the electric traits of many single cells at once in a 2024 paper. The traits differ between living and dead cells and between some cancer types, so a fast reader could sort cells for medicine and research. Their device pushes flowing particles between electrodes, where electric forces speed or slow each particle based on its traits.
A panel of small lights and a long strip detector track the particles without any lens or camera. Tests with plastic beads showed the device can resolve trait differences fine enough, on paper, to split viable from dead cells. With hamster ovary cells, it gathered a full response curve for many cells within minutes. The wide, clog-resistant channels promise cheap, high-volume cell checks.
Catalog record
| CREATOR | Emerich Kovacs, Behnam Arzang, Elham Salimi, Michael Butler, Greg E Bridges, Douglas J Thomson, Arunas Ramanavicius |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |