Veratridine Induces Vasorelaxation in Mouse Cecocolic Mesenteric Arteries
Joohee Park, Christina Sahyoun, Jacinthe Frangieh, Léa Réthoré, Coralyne Proux, Linda Grimaud, Emilie Vessières, Jennifer Bourreau, César Mattei, Daniel Henrion, Céline Marionneau, Ziad Fajloun, Claire Legendre, Christian Legros · 2024
Read Veratridine Induces Vasorelaxation in Mouse Cecocolic Mesenteric Arteries by Joohee Park, Christina Sahyoun, Jacinthe Frangieh, Léa Réthoré, Coralyne Proux, Linda Grimaud, Emilie Vessières, Jennifer Bourreau, César Mattei, Daniel Henrion, Céline Marionneau, Ziad Fajloun, Claire Legendre, Christian Legros (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11679225.txt.
Description
Joohee Park and co-authors study, in 2024, how a plant toxin relaxes a mouse gut artery. The toxin switches on sodium channels and is a common lab tool for blood vessel work. Earlier work showed such channels help set vessel tone. The team used wire myography on small resistance arteries from the mouse gut.
The toxin relaxed the arteries, and that effect vanished with blockers of sodium channels, of a nitric oxide enzyme, or of a common receptor for a nerve transmitter. Low sodium also stopped it. The authors conclude the toxin triggers nerve release of that transmitter, which switches on the vessel lining's relaxing machinery. A sodium-calcium exchanger in lining cells plays a part.
Catalog record
| CREATOR | Joohee Park, Christina Sahyoun, Jacinthe Frangieh, Léa Réthoré, Coralyne Proux, Linda Grimaud, Emilie Vessières, Jennifer Bourreau, César Mattei, Daniel Henrion, Céline Marionneau, Ziad Fajloun, Claire Legendre, Christian Legros |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 36 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |