PM2.5 Exposure Induces Glomerular Hyperfiltration in Mice in a Gender-Dependent Manner
Hao Wang, Li Ma, Yuqiong Guo, Lingyu Ren, Guangke Li, Nan Sang · 2024
Read PM2.5 Exposure Induces Glomerular Hyperfiltration in Mice in a Gender-Dependent Manner by Hao Wang, Li Ma, Yuqiong Guo, Lingyu Ren, Guangke Li, Nan Sang (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11679005.txt.
Description
Hao Wang and co-authors published a 2024 study of fine dust particles in the air, PM2.5, and early harm to the kidneys of mice. The dust is one of the most common air pollutants in the world. It raises risk in many body systems, the urinary system included. The team exposed male and female mice to the dust for eight weeks.
Kidney tests showed early harm in the females alone: their glomeruli, the filtering units, took in too much, a state of over-filtration marking strain. The glomeruli grew until they filled their capsules. Gene readings pointed to two drivers. A pressure tug-of-war between two cell systems fell out of balance, which raised pressure inside the glomeruli. Blood sugar also rose, which dulled a feedback brake on the inflow vessels. Both fed the strain. The study is a sex-specific warning about a pollutant people breathe.
Catalog record
| CREATOR | Hao Wang, Li Ma, Yuqiong Guo, Lingyu Ren, Guangke Li, Nan Sang |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 25 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |