The Role of Gene Expression Dysregulation in the Pathogenesis of Mucopolysaccharidosis: A Comparative Analysis of Shared and Specific Molecular Markers in Neuronopathic and Non-Neuronopathic Types of the Disease
Karolina Wiśniewska, Magdalena Żabińska, Aneta Szulc, Lidia Gaffke, Grzegorz Węgrzyn, Karolina Pierzynowska, Ritva Tikkanen · 2024
Read The Role of Gene Expression Dysregulation in the Pathogenesis of Mucopolysaccharidosis: A Comparative Analysis of Shared and Specific Molecular Markers in Neuronopathic and Non-Neuronopathic Types of the Disease by Karolina Wiśniewska, Magdalena Żabińska, Aneta Szulc, Lidia Gaffke, Grzegorz Węgrzyn, Karolina Pierzynowska, Ritva Tikkanen (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11678658.txt.
Description
Storage ills that clog cells share gene misreads, yet only some burn the brain, and Karolina Wiśniewska and co-authors compared the two kinds cell by cell, in work from twenty twenty-four. Patient cell cultures from many types of the ill were read by full gene sequencing. Shared and split misreads were sorted.
A few genes misread in nearly all types, which marks them as core to the disease. A second set misread only in the brain-burning types, which makes them candidate flags for early brain risk. No easy blood test exists today for that call. These lists give the hunt a start.
Catalog record
| CREATOR | Karolina Wiśniewska, Magdalena Żabińska, Aneta Szulc, Lidia Gaffke, Grzegorz Węgrzyn, Karolina Pierzynowska, Ritva Tikkanen |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |