Admixture of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Peripheral Nerve Blocks in Adolescents Undergoing Orthopedic Surgery: An Observational Cohort Study

Benjamin P. Fiorillo, M. Stephen Melton, Derek Nelsen, Lisa M. Einhorn · 2024

Read Admixture of Liposomal Bupivacaine and Bupivacaine Hydrochloride for Peripheral Nerve Blocks in Adolescents Undergoing Orthopedic Surgery: An Observational Cohort Study by Benjamin P. Fiorillo, M. Stephen Melton, Derek Nelsen, Lisa M. Einhorn (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11678512.txt.

Description

Fiorillo and co-authors reviewed, in a 2024 cohort study, a long-acting numbing mix used in nerve blocks for teenagers having bone surgery. The mix pairs liposomal bupivacaine, which releases slowly, with the standard fast form. One shot might then replace a catheter drip.

Charts from 2020 to 2024 covered 524 blocks in 374 patients aged 11 to 17, most in the lower limb. Forty percent needed two blocks for full coverage. Shoulder-area and thigh-canal blocks were the most common sites. A short survey after discharge added patients' own reports for part of the period. The authors map how this off-label technique is actually used in adolescents, a step toward judging its safety and value against catheter care.

Catalog record

CREATORBenjamin P. Fiorillo, M. Stephen Melton, Derek Nelsen, Lisa M. Einhorn
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11678512

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