Subcellular Localization Guides eNOS Function

Leticia Villadangos, Juan M Serrador, Tzong-Shyuan Lee · 2024

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Description

Villadangos and co-authors review in 2024 how the place of an enzyme inside a cell guides its work in making nitric oxide. That gas is a potent signal in body and disease, but it spreads fast and cannot be stored. Cells must thus control its making with care.

The enzyme form found in vessel lining is key for vessel health and heart disease. Where it sits inside the cell shapes its activity and how much gas is free to act. The review sums up early and recent work on what moves the enzyme between cell spots. It also weighs what those moves mean for health and disease.

Catalog record

CREATORLeticia Villadangos, Juan M Serrador, Tzong-Shyuan Lee
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE60 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11678294

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