How Tumors Affect Hemodynamics: A Diffusion Study on the Zebrafish Transplantable Model of Medullary Thyroid Carcinoma by Selective Plane Illumination Microscopy

Silvia Carra, Germano Gaudenzi, Giorgia Franceschetti, Maddalena Collini, Laura Sironi, Margaux Bouzin, Luca Persani, Giuseppe Chirico, Giovanni Vitale, Laura D’Alfonso · 2024

Read How Tumors Affect Hemodynamics: A Diffusion Study on the Zebrafish Transplantable Model of Medullary Thyroid Carcinoma by Selective Plane Illumination Microscopy by Silvia Carra, Germano Gaudenzi, Giorgia Franceschetti, Maddalena Collini, Laura Sironi, Margaux Bouzin, Luca Persani, Giuseppe Chirico, Giovanni Vitale, Laura D’Alfonso (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11678154.txt.

Description

Carra and nine co-authors gauge how a thyroid tumor bends blood flow in fish embryos in this twenty twenty-four study. This rare tumor grows rich vein nets and sheds growth scents to feed them. A fish graft rig lets the team watch that vein growth as it forms live.

Inside, a flat light scope reads glow bits as they drift through the graft veins. Flow spread in grafted young fish ran ten-fold slow next to sound kin fish. That gap marks a shift in how leaky the tumor veins are to blood bits. The rig gives a clean read of vein leak for this tumor type. The team casts it as a base for drug hunts on vein growth.

Catalog record

CREATORSilvia Carra, Germano Gaudenzi, Giorgia Franceschetti, Maddalena Collini, Laura Sironi, Margaux Bouzin, Luca Persani, Giuseppe Chirico, Giovanni Vitale, Laura D’Alfonso
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE41 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11678154

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