An Integrated Analysis of the Role of Gut Microbiome-Associated Metabolites in the Detection of MASH-Related Cirrhosis
Feixiang Xiong, Xuejie Zhang, Yuyong Jiang, Peipei Meng, Yang Zhou, Xiaomin Ji, Jialiang Chen, Tong Wu, Yixin Hou · 2024
Read An Integrated Analysis of the Role of Gut Microbiome-Associated Metabolites in the Detection of MASH-Related Cirrhosis by Feixiang Xiong, Xuejie Zhang, Yuyong Jiang, Peipei Meng, Yang Zhou, Xiaomin Ji, Jialiang Chen, Tong Wu, Yixin Hou (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11678040.txt.
Description
Feixiang Xiong and colleagues published a 2024 medical study on fatty liver disease and the gut. The team compared healthy people, patients with a serious form of fatty liver inflammation, and patients whose disease had advanced to scarring called cirrhosis. They wanted markers that could flag the cirrhosis stage without invasive testing.
Stool samples from ninety patients underwent gene sequencing and chemical analysis of the small molecules microbes produce. One bacterial family and genus, both lower in sicker patients, tracked disease progress most strongly in their models. The work points toward stool-based clues that might one day help doctors spot dangerous liver scarring earlier.
Catalog record
| CREATOR | Feixiang Xiong, Xuejie Zhang, Yuyong Jiang, Peipei Meng, Yang Zhou, Xiaomin Ji, Jialiang Chen, Tong Wu, Yixin Hou |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 26 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |