The Formulation and Evaluation of Customized Prednisolone Gel Tablets Prepared by an Automated Extrusion-Based Material Deposition Method
Marina Tihhonova, Andres Meos, Sari Airaksinen, Jaan Aruväli, Niklas Sandler Topelius, Jyrki Heinämäki, Urve Paaver · 2024
Read The Formulation and Evaluation of Customized Prednisolone Gel Tablets Prepared by an Automated Extrusion-Based Material Deposition Method by Marina Tihhonova, Andres Meos, Sari Airaksinen, Jaan Aruväli, Niklas Sandler Topelius, Jyrki Heinämäki, Urve Paaver (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11677990.txt.
Description
Marina Tihhonova and six co-authors test a machine that prints custom drug tablets in a study from 2024. The printer squeezes out a soft gel layer by layer to form tablets with exact doses. Their test drug was prednisolone, a steroid used here with pets in mind, since dogs and cats need doses that standard tablets do not match.
Printed tablets hit their target weights closely and had smooth, even shapes. The drug changed its crystal form inside the gel but released fast, with most of the dose out within thirty minutes. Drug content held steady over three months of storage. The method suits pet, child, and personal dosing.
Catalog record
| CREATOR | Marina Tihhonova, Andres Meos, Sari Airaksinen, Jaan Aruväli, Niklas Sandler Topelius, Jyrki Heinämäki, Urve Paaver |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |