Sustained Release of Curcumin from Cur-LPs Loaded Adaptive Injectable Self-Healing Hydrogels
Caixia Wu, Xiaoqun Ning, Qunfeng Liu, Xiaoyan Zhou, Huilong Guo, Denise Freitas Siqueira Petri, Dimitrios Bikiaris · 2024
Read Sustained Release of Curcumin from Cur-LPs Loaded Adaptive Injectable Self-Healing Hydrogels by Caixia Wu, Xiaoqun Ning, Qunfeng Liu, Xiaoyan Zhou, Huilong Guo, Denise Freitas Siqueira Petri, Dimitrios Bikiaris (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11677872.txt.
Description
Caixia Wu and co-authors build an injectable, self healing gel that slowly releases curcumin for tissue repair in a 2024 study. Wounds with odd shapes are hard to fill, and they often suffer swelling and excess reactive oxygen. The gel sets within thirty seconds, sticks to tissue, and moves with it.
It is formed from modified natural polymers linked by dynamic bonds, and it carries curcumin packed in tiny fat spheres near 180 nanometers wide. Tests showed good cell safety and strong free radical clearing. Release lasted ten days, far longer than free curcumin would allow. The authors see the gel as a candidate for filling and healing irregular tissue defects.
Catalog record
| CREATOR | Caixia Wu, Xiaoqun Ning, Qunfeng Liu, Xiaoyan Zhou, Huilong Guo, Denise Freitas Siqueira Petri, Dimitrios Bikiaris |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |