Can Serum and Saliva Inflammatory Cytokines Be Considered a Reliable Marker in Chronic Oral Graft-Versus-Host Disease Patients?
Giorgia Pugliese, Letizia Nitro, Fabiana Allevi, Federico Biglioli, Matilde Coccapani, Giovanni Felisati, Francesco Ferella, Giorgio Ghilardi, Linda Montavoci, Anna Caretti, Alberto Maria Saibene, Herng-Ching Lin · 2024
Read Can Serum and Saliva Inflammatory Cytokines Be Considered a Reliable Marker in Chronic Oral Graft-Versus-Host Disease Patients? by Giorgia Pugliese, Letizia Nitro, Fabiana Allevi, Federico Biglioli, Matilde Coccapani, Giovanni Felisati, Francesco Ferella, Giorgio Ghilardi, Linda Montavoci, Anna Caretti, Alberto Maria Saibene, Herng-Ching Lin (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11677514.txt.
Description
Giorgia Pugliese and co-authors test whether inflammatory cytokines can mark chronic oral graft versus host disease in a 2024 study. The condition inflames the mouth after transplantation and resembles oral lichen planus, making diagnosis tricky. A reliable blood or saliva marker would help separate the two.
Patients with the graft disease, patients with lichen planus, and healthy controls gave serum and saliva samples. Three cytokines were measured and compared across groups. One, IL-17, was significantly higher in serum of graft disease patients. Saliva did not prove reliable. The authors call for larger studies to validate the preliminary signal.
Catalog record
| CREATOR | Giorgia Pugliese, Letizia Nitro, Fabiana Allevi, Federico Biglioli, Matilde Coccapani, Giovanni Felisati, Francesco Ferella, Giorgio Ghilardi, Linda Montavoci, Anna Caretti, Alberto Maria Saibene, Herng-Ching Lin |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 21 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |