Quality by Design Approach for the Formulation and Evaluation of Stem Cells Derived Rosmarinic Acid-Loaded Nanofibers as an Anti-Wrinkle Patch: In Vitro and In Vivo Characterizations
Rehab Abdelmonem, Ahmed Bakr, Ingy Badawy, Ahmed Ibrahim Abd El Maksoud, Reem T. Attia · 2024
Read Quality by Design Approach for the Formulation and Evaluation of Stem Cells Derived Rosmarinic Acid-Loaded Nanofibers as an Anti-Wrinkle Patch: In Vitro and In Vivo Characterizations by Rehab Abdelmonem, Ahmed Bakr, Ingy Badawy, Ahmed Ibrahim Abd El Maksoud, Reem T. Attia (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11677431.txt.
Description
Rehab Abdelmonem and co-authors build an anti-wrinkle patch from plant stem cells in a 2024 study. Wrinkles follow from many aging processes, and plant extracts are a renewable cosmetic source. Their plant, a medicinal sage, makes rosmarinic acid, a compound proposed to smooth skin.
Using a quality-by-design plan, the team grew plant callus tissue and tested two signal chemicals that push cells to make more of the compound. One dose raised the yield to sixteen milligrams per gram. The extract then went into a nanofiber patch, tested in the lab and in living skin for release and effect. A patch delivering a plant active in measured doses is the goal.
Catalog record
| CREATOR | Rehab Abdelmonem, Ahmed Bakr, Ingy Badawy, Ahmed Ibrahim Abd El Maksoud, Reem T. Attia |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 44 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |