TRAIL as a Warrior in Nano-Sized Trojan Horse: Anticancer and Anti-Metastatic Effects of Nano-Formulations of TRAIL in Cell Culture and Animal Model Studies
Ammad Ahmad Farooqi, Assiya Turgambayeva, Gulnara Kamalbekova, Roza Suleimenova, Natalya Latypova, Sholpan Ospanova, Dinara Ospanova, Zhanat Abdikadyr, Sabit Zhussupov, Saulius Šatkauskas, Darko Katalinić, Ivana Škrlec · 2024
Read TRAIL as a Warrior in Nano-Sized Trojan Horse: Anticancer and Anti-Metastatic Effects of Nano-Formulations of TRAIL in Cell Culture and Animal Model Studies by Ammad Ahmad Farooqi, Assiya Turgambayeva, Gulnara Kamalbekova, Roza Suleimenova, Natalya Latypova, Sholpan Ospanova, Dinara Ospanova, Zhanat Abdikadyr, Sabit Zhussupov, Saulius Šatkauskas, Darko Katalinić, Ivana Škrlec (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11677168.txt.
Description
Ammad Ahmad Farooqi and co-authors review nano-sized carriers for a cancer-killing protein called TRAIL, in a review from 2024. TRAIL can trigger death in cancer cells while sparing most healthy ones, a rare and prized trait. Trials of TRAIL drugs have reached middle and late phases.
The protein's weakness is delivery: it clears from the body fast and reaches tumors poorly. Loading it into nano carriers, the Trojan horse of the title, aims to fix that. Cell and animal studies of these packaged forms show stronger cancer killing and less spread to new sites. The review gathers that evidence and the pathway knowledge behind it. The authors see packaged TRAIL as a live direction for cancer therapy design.
Catalog record
| CREATOR | Ammad Ahmad Farooqi, Assiya Turgambayeva, Gulnara Kamalbekova, Roza Suleimenova, Natalya Latypova, Sholpan Ospanova, Dinara Ospanova, Zhanat Abdikadyr, Sabit Zhussupov, Saulius Šatkauskas, Darko Katalinić, Ivana Škrlec |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 47 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |