Establishment of Novel High-Grade Serous Ovarian Carcinoma Cell Line OVAR79
Polina V. Shnaider, Irina K. Malyants, Olga M. Ivanova, Veronika S. Gordeeva, Ekaterina A. Svirina, Natalya B. Zakharzhevskaya, Olga Y. Shagaleeva, Oksana V. Selezneva, Alexandra N. Bogomazova, Maria M. Lukina, Olga I. Aleshikova, Nataliya A. Babaeva, Andrey V. Slonov, Victoria O. Shender · 2024
Read Establishment of Novel High-Grade Serous Ovarian Carcinoma Cell Line OVAR79 by Polina V. Shnaider, Irina K. Malyants, Olga M. Ivanova, Veronika S. Gordeeva, Ekaterina A. Svirina, Natalya B. Zakharzhevskaya, Olga Y. Shagaleeva, Oksana V. Selezneva, Alexandra N. Bogomazova, Maria M. Lukina, Olga I. Aleshikova, Nataliya A. Babaeva, Andrey V. Slonov, Victoria O. Shender (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11676670.txt.
Description
Polina Shnaider and co-authors introduce a new ovarian cancer cell line in a 2024 paper. High-grade serous ovarian carcinoma is the most common and deadly form of ovarian cancer. Lab cell lines often fail to mirror its tangled genetics, which limits what experiments can teach. The new line, OVAR79, was grown from fluid taken from a patient with this cancer.
The line carries an unusual mix of gene changes, including mutations in two growth-control genes and heavy chromosome instability. It also grows fast, is easy to keep, and takes up added DNA very well. The team compared its growth, movement, and drug response with two widely used ovarian lines. They offer OVAR79 as a fresh, handy model for basic and applied ovarian cancer research.
Catalog record
| CREATOR | Polina V. Shnaider, Irina K. Malyants, Olga M. Ivanova, Veronika S. Gordeeva, Ekaterina A. Svirina, Natalya B. Zakharzhevskaya, Olga Y. Shagaleeva, Oksana V. Selezneva, Alexandra N. Bogomazova, Maria M. Lukina, Olga I. Aleshikova, Nataliya A. Babaeva, Andrey V. Slonov, Victoria O. Shender |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 29 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |