Visualizing the Tumor Microenvironment: Molecular Imaging Probes Target Extracellular Matrix, Vascular Networks, and Immunosuppressive Cells
Hui-Wen Chan, Deng-Yu Kuo, Pei-Wei Shueng, Hui-Yen Chuang, Cécile Philippe · 2024
Read Visualizing the Tumor Microenvironment: Molecular Imaging Probes Target Extracellular Matrix, Vascular Networks, and Immunosuppressive Cells by Hui-Wen Chan, Deng-Yu Kuo, Pei-Wei Shueng, Hui-Yen Chuang, Cécile Philippe (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11676442.txt.
Description
Hui-Wen Chan and co-authors review, in a 2024 paper, imaging tools that light up the neighborhood a tumor lives in. That microenvironment drives growth, helps the tumor hide from the immune system, and feeds resistance and spread. Scanning it without cutting offers a live, repeatable view. The review covers three families of techniques, from radioactive tracers to magnetic resonance to glowing dyes used in surgery.
The heart of the paper is the probes: molecules built to home in on one feature of the neighborhood. Some target the scaffolding matrix between cells. Others mark the blood vessel networks, or the immune cells the tumor has turned into bodyguards. The authors argue these tools can sharpen early diagnosis and track treatment as it works. They frame molecular imaging as a pillar of precision oncology.
Catalog record
| CREATOR | Hui-Wen Chan, Deng-Yu Kuo, Pei-Wei Shueng, Hui-Yen Chuang, Cécile Philippe |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 56 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |