Cadmium-Induced Oxidative Damage and the Expression and Function of Mitochondrial Thioredoxin in Phascolosoma esculenta

Shenwei Gu, Xuebin Zheng, Xinming Gao, Yang Liu, Yiner Chen, Junquan Zhu, Toshiyuki Kaji · 2024

Read Cadmium-Induced Oxidative Damage and the Expression and Function of Mitochondrial Thioredoxin in Phascolosoma esculenta by Shenwei Gu, Xuebin Zheng, Xinming Gao, Yang Liu, Yiner Chen, Junquan Zhu, Toshiyuki Kaji (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11676412.txt.

Description

Shenwei Gu and co-authors study cadmium poisoning and a protective protein in a sea worm in a 2024 paper. The peanut worm lives in polluted Chinese coastal mud. Its mitochondrial thioredoxin fights oxidative damage. Cadmium is a common coastal toxin.

Under cadmium, gut enzyme defenses swung and damage markers rose. After four days, tissue showed holes, dying cells, and eaten mitochondria. The protective gene first surged, then faded with longer stress. Its pure protein quenched oxidants and helped bacteria survive cadmium. Silencing the gene shifted death-pathway genes. The protein is a linchpin of the worm's detox defense.

Catalog record

CREATORShenwei Gu, Xuebin Zheng, Xinming Gao, Yang Liu, Yiner Chen, Junquan Zhu, Toshiyuki Kaji
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11676412

Browse the full library · About the Tower of Babel