Optimized Extraction of Sargahydroquinoic Acid, Major Bioactive Substance, from Sargassum yezoense Using Response Surface Methodology

Suhyeon Baek, Ji-Eun Bae, Yu Miao, Gahyeon Kim, Bomi Ryu, Byung-Hoo Lee, Sanggil Lee · 2024

Read Optimized Extraction of Sargahydroquinoic Acid, Major Bioactive Substance, from Sargassum yezoense Using Response Surface Methodology by Suhyeon Baek, Ji-Eun Bae, Yu Miao, Gahyeon Kim, Bomi Ryu, Byung-Hoo Lee, Sanggil Lee (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11676218.txt.

Description

Suhyeon Baek and six co-authors published a study in 2024 on squeezing the most of a health compound out of brown seaweed, and proving the extract fights oxidation. The compound, sargahydroquinoic acid, comes from Sargassum yezoense and carries notable bioactivity. Three knobs govern its yield: temperature, time, and alcohol strength.

A response-surface design mapped the knobs together and landed on about fifty-three degrees, eight hours, and seventy-four percent ethanol. The tuned extract carried about sixty-eight milligrams of the compound per gram and scored well across three standard antioxidant tests. In zebrafish stressed with peroxide, the extract and the pure compound both suppressed damaging oxygen radicals. A first recipe, the authors note, for an ingredient with supplement potential.

Catalog record

CREATORSuhyeon Baek, Ji-Eun Bae, Yu Miao, Gahyeon Kim, Bomi Ryu, Byung-Hoo Lee, Sanggil Lee
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE29 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11676218

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