Endothelial Dysfunction: Molecular Mechanisms and Therapeutic Strategies in Kawasaki Disease

Lucia Paolini, Fiorentina Guida, Antonino Calvaruso, Laura Andreozzi, Luca Pierantoni, Marcello Lanari, Marianna Fabi · 2024

Read Endothelial Dysfunction: Molecular Mechanisms and Therapeutic Strategies in Kawasaki Disease by Lucia Paolini, Fiorentina Guida, Antonino Calvaruso, Laura Andreozzi, Luca Pierantoni, Marcello Lanari, Marianna Fabi (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11676170.txt.

Description

Lucia Paolini and co-authors review how vessel lining failure drives Kawasaki disease. Their 2024 paper deals with a childhood vasculitis that tops the list of gained heart disease in children, through coronary harm. The endothelium, the vessel's inner skin, steers vessel balance by answering chemical and physical cues. In Kawasaki disease that skin falters as vessels inflame.

The review maps the molecular steps of the failure and what they mean for care. Knowing the steps names drug targets that could spare hearts in both the hot phase and the long tail. Animal-to-clinic gaps remain, they grant.

Catalog record

CREATORLucia Paolini, Fiorentina Guida, Antonino Calvaruso, Laura Andreozzi, Luca Pierantoni, Marcello Lanari, Marianna Fabi
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE28 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11676170

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