3D Bioprintable Self-Healing Hyaluronic Acid Hydrogel with Cysteamine Grafting for Tissue Engineering

Kasula Nagaraja, Amitava Bhattacharyya, Minsik Jung, Dajeong Kim, Mst Rita Khatun, Insup Noh, Chuanliang Feng · 2024

Read 3D Bioprintable Self-Healing Hyaluronic Acid Hydrogel with Cysteamine Grafting for Tissue Engineering by Kasula Nagaraja, Amitava Bhattacharyya, Minsik Jung, Dajeong Kim, Mst Rita Khatun, Insup Noh, Chuanliang Feng (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11675811.txt.

Description

Kasula Nagaraja and co-authors build a printable gel for growing replacement tissue, in a 2024 study. The gel rests on hyaluronic acid, a sugar chain found all over the human body. Turning it into a printer ink is tricky: light-set versions can involve harsh chemicals, and soft gels collapse when printed in fine shapes.

Their design links the acid chains two ways at once, adding a grafted helper molecule for the second link. The result prints through a nozzle into complex shapes that stand on their own. The gel stayed stable in warm salt water for over six weeks, drank up water without swelling much, and could heal its own cuts. Self-healing, sticky gels like this suit wound care and tissue building.

Catalog record

CREATORKasula Nagaraja, Amitava Bhattacharyya, Minsik Jung, Dajeong Kim, Mst Rita Khatun, Insup Noh, Chuanliang Feng
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE40 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11675811

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