Transcriptome Analysis Reveals Sertoli Cells Adapting Through Redox and Metabolic Pathways Under Heat Stress in Goats
Guang Yang, Yiwei Wang, Pengyun Ji, Bingyuan Wang, Guoshi Liu, Yan Xiong, Yaqiu Lin · 2024
Read Transcriptome Analysis Reveals Sertoli Cells Adapting Through Redox and Metabolic Pathways Under Heat Stress in Goats by Guang Yang, Yiwei Wang, Pengyun Ji, Bingyuan Wang, Guoshi Liu, Yan Xiong, Yaqiu Lin (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11675638.txt.
Description
Guang Yang and co-authors read the gene activity of goat testis cells under heat stress, in a 2024 paper. The head byline lists five names while the catalog lists seven. Hot weather cuts livestock fertility, and Sertoli cells, the nurse cells of sperm production, sit in the blast.
Cells from young black goats were baked at 44 degrees for two and a half hours. Viability fell, oxidative stress rose, and self-eating structures multiplied. Sequencing found 1,231 genes switching level, clustered in membrane and metabolism pathways. Sugar and fat handling genes dropped. A network analysis flagged ten hub genes, several being heat-shock veterans. The map suggests how the cells ride out the insult, and where protection fails.
Catalog record
| CREATOR | Guang Yang, Yiwei Wang, Pengyun Ji, Bingyuan Wang, Guoshi Liu, Yan Xiong, Yaqiu Lin |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 31 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |