Forensic STR Loci and Schizophrenia: An Exploration of Implications for Forensic Applications and Genetic Privacy

Qi Yang, Chun Yang, Zhiqi Hua, Qi Shen, Anqi Chen, Huajie Ba, Suhua Zhang, Mitchell Mark Holland, Fulvio Cruciani · 2024

Read Forensic STR Loci and Schizophrenia: An Exploration of Implications for Forensic Applications and Genetic Privacy by Qi Yang, Chun Yang, Zhiqi Hua, Qi Shen, Anqi Chen, Huajie Ba, Suhua Zhang, Mitchell Mark Holland, Fulvio Cruciani (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11675584.txt.

Description

Yang and a team including Holland and Cruciani present a study from twenty twenty-four on forensic DNA markers and schizophrenia. Forensic identification uses short repeat markers picked to avoid medical links. Some reports tie two such markers to mental illness risk. The team test nineteen markers in patients and matched controls. Early looks show small frequency gaps at three markers. After strict correction for many tests, no marker links to schizophrenia. The null result holds across the full marker set.

The authors still flag privacy stakes for forensic databases. DNA kept for identity could someday reveal health traits. Expanding databases need fresh ethical and legal review, they argue. Larger, more varied samples should test the question further.

Catalog record

CREATORQi Yang, Chun Yang, Zhiqi Hua, Qi Shen, Anqi Chen, Huajie Ba, Suhua Zhang, Mitchell Mark Holland, Fulvio Cruciani
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE27 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11675584

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