A Decade of Non-Invasive Prenatal Testing (NIPT) for Chromosomal Abnormalities in Croatia: First National Monocentric Study to Inform Country’s Future Prenatal Care Strategy
Petra Podobnik, Tomislav Meštrović, Aida Đorđević, Kristian Kurdija, Dženis Jelčić, Nina Ogrin, Ivan Bertović-Žunec, Beata Gebauer-Vuković, Grega Hočevar, Igor Lončar, Zlata Srebreniković, Petra Trobina, Marko Bitenc, Ivo Dumić-Čule, Sung Sam Gong, Maria Piccione · 2024
Read A Decade of Non-Invasive Prenatal Testing (NIPT) for Chromosomal Abnormalities in Croatia: First National Monocentric Study to Inform Country’s Future Prenatal Care Strategy by Petra Podobnik, Tomislav Meštrović, Aida Đorđević, Kristian Kurdija, Dženis Jelčić, Nina Ogrin, Ivan Bertović-Žunec, Beata Gebauer-Vuković, Grega Hočevar, Igor Lončar, Zlata Srebreniković, Petra Trobina, Marko Bitenc, Ivo Dumić-Čule, Sung Sam Gong, Maria Piccione (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11675109.txt.
Description
Podobnik and co-authors chart a decade of blood-based prenatal screening in Croatia. The test reads fetal DNA fragments in a mother's blood to flag chromosome disorders without risking the pregnancy. Reviewing 2,431 tests from 2013 to 2023 at one specialist hospital, the team tracked who came, how fast results returned, and what turned up.
The service matured visibly. Average turnaround fell from over twelve days to about seven. The typical mother grew younger, from 36 to 33, hinting the test spread beyond older, high-risk pregnancies. Among high-risk results, 39 abnormalities emerged, three in five of them Down syndrome. The authors urge folding the test into public care so access stops depending on wealth.
Catalog record
| CREATOR | Petra Podobnik, Tomislav Meštrović, Aida Đorđević, Kristian Kurdija, Dženis Jelčić, Nina Ogrin, Ivan Bertović-Žunec, Beata Gebauer-Vuković, Grega Hočevar, Igor Lončar, Zlata Srebreniković, Petra Trobina, Marko Bitenc, Ivo Dumić-Čule, Sung Sam Gong, Maria Piccione |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 40 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |