Real-World Efficacy and Adherence to Palbociclib in HR-Positive, HER2-Negative Advanced Breast Cancer: Insights from a Romanian Cohort
Cristian Virgil Lungulescu, Georgiana-Cristiana Camen, Mihaela-Simona Naidin, Tradian-Ciprian Berisha, Andrei Bita, Venera-Cristina Dinescu, Sandra Alice Buteica, Marina-Daniela Dimulescu, Simona Ruxandra Volovat, Adina Turcu-Stiolica, Hiroaki Kiyokawa · 2024
Read Real-World Efficacy and Adherence to Palbociclib in HR-Positive, HER2-Negative Advanced Breast Cancer: Insights from a Romanian Cohort by Cristian Virgil Lungulescu, Georgiana-Cristiana Camen, Mihaela-Simona Naidin, Tradian-Ciprian Berisha, Andrei Bita, Venera-Cristina Dinescu, Sandra Alice Buteica, Marina-Daniela Dimulescu, Simona Ruxandra Volovat, Adina Turcu-Stiolica, Hiroaki Kiyokawa (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11674954.txt.
Description
Cristian Virgil Lungulescu and co-authors check a breast cancer drug in everyday Romanian care in this 2024 study. Palbociclib, paired with hormone therapy, treats hormone-positive, HER2-negative advanced breast cancer. Trials proved it under controlled conditions; clinics asked how it performs in the wild.
Romania began reimbursing the drug in July 2018. The team mined insurance records from Dolj County through 2023. They measured how well the drug worked, its side effects, and whether patients stayed on it. Real-world adherence often decides real-world benefit. The cohort gives smaller health systems evidence from their own setting, not just trial centers.
Catalog record
| CREATOR | Cristian Virgil Lungulescu, Georgiana-Cristiana Camen, Mihaela-Simona Naidin, Tradian-Ciprian Berisha, Andrei Bita, Venera-Cristina Dinescu, Sandra Alice Buteica, Marina-Daniela Dimulescu, Simona Ruxandra Volovat, Adina Turcu-Stiolica, Hiroaki Kiyokawa |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 32 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |