Biotechnology Revolution Shaping the Future of Diabetes Management

Nilima Rajpal Kundnani, Bogdan Lolescu, Anca-Raluca Dinu, Delia Mira Berceanu-Vaduva, Patrick Dumitrescu, Tudor-Paul Tamaș, Abhinav Sharma, Mihaela-Diana Popa · 2024

Read Biotechnology Revolution Shaping the Future of Diabetes Management by Nilima Rajpal Kundnani, Bogdan Lolescu, Anca-Raluca Dinu, Delia Mira Berceanu-Vaduva, Patrick Dumitrescu, Tudor-Paul Tamaș, Abhinav Sharma, Mihaela-Diana Popa (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11674738.txt.

Description

Diabetes care changed slowly for centuries, then biotechnology rewrote it within a few decades. Eight authors trace that story in a 2024 review. It runs from ancient mentions of the disease to the insulin sequence of the 1950s and lab-made human insulin in 1982. From there they survey designer insulins and newer peptide drugs that act on gut hormone receptors, sometimes several at once.

The review then covers hardware: insulin pumps, continuous glucose monitors, and systems that dose insulin on their own. It closes with cell-based hopes, including transplanted islet cells, lab-grown organoids, and efforts to rebuild the pancreas itself. Each step, the authors argue, tightens control of blood sugar for patients.

Catalog record

CREATORNilima Rajpal Kundnani, Bogdan Lolescu, Anca-Raluca Dinu, Delia Mira Berceanu-Vaduva, Patrick Dumitrescu, Tudor-Paul Tamaș, Abhinav Sharma, Mihaela-Diana Popa
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE55 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11674738

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