Urinary MicroRNA-21 for Prostate Cancer Detection Using a Silver Nanoparticle Sensor: A Promising Diagnostic Tool

See-Tong Pang, Yueh-Er Chiou, Jasmine Lim, Yi-Chun Zhang, Wen-Zhen Zeng, Teng Aik Ong, Wen-Hui Weng · 2024

Read Urinary MicroRNA-21 for Prostate Cancer Detection Using a Silver Nanoparticle Sensor: A Promising Diagnostic Tool by See-Tong Pang, Yueh-Er Chiou, Jasmine Lim, Yi-Chun Zhang, Wen-Zhen Zeng, Teng Aik Ong, Wen-Hui Weng (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11674719.txt.

Description

See-Tong Pang and co-authors test a urine sensor for a small RNA that may flag prostate cancer. Their 2024 study measures microRNA-21, a molecule whose levels shift in several cancers. The sensor is built on silver nanoparticles and aims for a simple, non-invasive screen.

Thirty-eight urine samples came from ten cancer patients at three points around surgery, plus men with benign prostate growth and healthy controls. The sensor agreed with a standard lab test and could detect very low levels with good selectivity. Levels of the marker fell sharply three months after surgery in cancer patients. Cancer and benign groups both differed clearly from healthy men. The authors propose the sensor as a helper for early detection.

Catalog record

CREATORSee-Tong Pang, Yueh-Er Chiou, Jasmine Lim, Yi-Chun Zhang, Wen-Zhen Zeng, Teng Aik Ong, Wen-Hui Weng
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE35 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11674719

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