Genetic Associations of TCF7L2 (rs7903146) and PPARG (rs1801282) with Prediabetes in the Ethnic Kazakh Population
Azhar Dyussupova, Gulnara Svyatova, Galina Berezina, Altay Dyussupov, Bauyrzhan Omarkulov, Anastassiya Dzharmukhametova, Oxana Yurkovskaya, Venera Akhmetova, Asylzhan Dyussupova · 2024
Read Genetic Associations of TCF7L2 (rs7903146) and PPARG (rs1801282) with Prediabetes in the Ethnic Kazakh Population by Azhar Dyussupova, Gulnara Svyatova, Galina Berezina, Altay Dyussupov, Bauyrzhan Omarkulov, Anastassiya Dzharmukhametova, Oxana Yurkovskaya, Venera Akhmetova, Asylzhan Dyussupova (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11674111.txt.
Description
Azhar Dyussupova and co-authors present a 2024 case-control study of two famous diabetes genes in ethnic Kazakh people with prediabetes. Variants in TCF7L2 and PPARG raise diabetes risk in many populations. Their role at that early stage in Kazakhstan was unmeasured.
Two hundred cases with prediabetes and two hundred matched controls had their genes typed by targeted tests. Cases carried higher birth weight, body mass, and waist measures. Both gene variants clearly raised prediabetes risk in this group. Early genetic screening could flag Kazakh adults for stronger lifestyle prevention before full diabetes develops.
Catalog record
| CREATOR | Azhar Dyussupova, Gulnara Svyatova, Galina Berezina, Altay Dyussupov, Bauyrzhan Omarkulov, Anastassiya Dzharmukhametova, Oxana Yurkovskaya, Venera Akhmetova, Asylzhan Dyussupova |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 28 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |