Extracellular Vesicles from Plasma of Patients with Glioblastoma Promote Invasion of Glioblastoma Cells Even After Tumor Resection

Ekaterina N Lyukmanova, Artem V Kirichenko, Igor A Medyanik, Konstantin S Yashin, Mikhail P Kirpichnikov, Maxim L Bychkov, Dimitrios Kanakis · 2024

Read Extracellular Vesicles from Plasma of Patients with Glioblastoma Promote Invasion of Glioblastoma Cells Even After Tumor Resection by Ekaterina N Lyukmanova, Artem V Kirichenko, Igor A Medyanik, Konstantin S Yashin, Mikhail P Kirpichnikov, Maxim L Bychkov, Dimitrios Kanakis (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11673896.txt.

Description

Ekaterina Lyukmanova and co-authors studied tiny parcels released by glioblastoma tumors in 2024. Glioblastoma is a fast-growing brain tumor. Its parcels can cross into the blood and carry signals that help the tumor spread.

The team took parcels from blood plasma of healthy donors and from patients before and after tumor surgery. They tested how those parcels affected normal brain support cells and tumor cells. Healthy parcels did not raise invasion. Parcels taken before surgery raised invasion in tumor cells and switched on growth pathways. Parcels taken after surgery kept most of those harmful effects. The work hints that tumor signals in blood can persist after the tumor is removed.

Catalog record

CREATOREkaterina N Lyukmanova, Artem V Kirichenko, Igor A Medyanik, Konstantin S Yashin, Mikhail P Kirpichnikov, Maxim L Bychkov, Dimitrios Kanakis
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11673896

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