Repurposing Historic Drugs for Neutrophil-Mediated Inflammation in Skin Disorders
Ludovica Franceschin, Alessia Guidotti, Roberto Mazzetto, Jacopo Tartaglia, Christian Ciolfi, Mauro Alaibac, Alvise Sernicola, Angelo Valerio Marzano, Sergio Crovella, Chiara Moltrasio · 2024
Read Repurposing Historic Drugs for Neutrophil-Mediated Inflammation in Skin Disorders by Ludovica Franceschin, Alessia Guidotti, Roberto Mazzetto, Jacopo Tartaglia, Christian Ciolfi, Mauro Alaibac, Alvise Sernicola, Angelo Valerio Marzano, Sergio Crovella, Chiara Moltrasio (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11673839.txt.
Description
Some skin ills are driven by neutrophils, the blood's first rushers, and a shelf of old drugs can calm them. Franceschin and co-authors review that shelf in 2024. Three veterans lead it: a leprosy drug, a gout drug, and a family of antibiotics, all credited with strong anti-rusher force.
Their uses run wide: blistering autoimmune ills, pus-heavy skin states, and grainy growths among them. Most uses are off-label, backed by lone reports and short series, not by trials. How the rushers drive each ill is still half-mapped, the authors grant. The review gathers the scattered proof into one place, so a skin doctor can weigh an old, cheap drug before a dear new one.
Catalog record
| CREATOR | Ludovica Franceschin, Alessia Guidotti, Roberto Mazzetto, Jacopo Tartaglia, Christian Ciolfi, Mauro Alaibac, Alvise Sernicola, Angelo Valerio Marzano, Sergio Crovella, Chiara Moltrasio |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |