Alarmins in Chronic Spontaneous Urticaria: Immunological Insights and Therapeutic Perspectives

Angela Rizzi, Federica Li Pomi, Riccardo Inchingolo, Marinella Viola, Francesco Borgia, Sebastiano Gangemi · 2024

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Description

Angela Rizzi and five co-authors review alarm signals of the immune system in chronic hives with no clear trigger, in a paper from 2024. About one in a hundred people live with this itchy state, which strains daily life and care.

Alarmins are molecules freed by stressed cells that wake immune replies. Two skin born alarmins stand out as hopeful marks for spotting and grading the state, and as drug targets. Proof for other alarmins, from heat shock proteins to cell waste signs, is more mixed. The authors call for larger, shared cohort studies and world registries to sort the field.

Catalog record

CREATORAngela Rizzi, Federica Li Pomi, Riccardo Inchingolo, Marinella Viola, Francesco Borgia, Sebastiano Gangemi
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE38 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11673798

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