From Molecules to Amoeboid Movement: A New Way for Understanding the Morphology Through Actin-Binding Proteins
Ekaterina Volkova, Igor Pozdnyakov, Mikhail Petukhov, Valeriia Polezhaeva · 2024
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Description
Ekaterina Volkova, Igor Pozdnyakov, Mikhail Petukhov, and Valeriia Polezhaeva link cell shape in amoebae to a protein complex in a 2024 paper. Amoebae crawl by changing shape, and each group keeps a set form while moving. A scaffold protein called actin drives that motion, helped by partner proteins that join its strands at an angle.
The team modeled a key partner complex for thirty species and estimated how tightly its two parts bind. Species with a broad clear front zone bound most loosely, while those with no clear zone bound most tightly. The authors say the pattern gives new insight into how moving cell shape is built.
Catalog record
| CREATOR | Ekaterina Volkova, Igor Pozdnyakov, Mikhail Petukhov, Valeriia Polezhaeva |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 35 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |