Maternal Low-Protein Diet During Nursing Leads to Glucose–Insulin Dyshomeostasis and Pancreatic-Islet Dysfunction by Disrupting Glucocorticoid Responsiveness in Male Rats
Paulo Cezar de Freitas Mathias, Aline Milena Dantas Rodrigues, Patrícia Cristina Lisboa, Rosiane Aparecida Miranda, Ananda Malta, Tatiane Aparecida Ribeiro, Luiz Felipe Barella, Ginislene Dias, Thalyne Aparecida Leite Lima, Rodrigo Mello Gomes, Egberto Gaspar de Moura, Júlio Cezar de Oliveira, Seiho · 2024
Read Maternal Low-Protein Diet During Nursing Leads to Glucose–Insulin Dyshomeostasis and Pancreatic-Islet Dysfunction by Disrupting Glucocorticoid Responsiveness in Male Rats by Paulo Cezar de Freitas Mathias, Aline Milena Dantas Rodrigues, Patrícia Cristina Lisboa, Rosiane Aparecida Miranda, Ananda Malta, Tatiane Aparecida Ribeiro, Luiz Felipe Barella, Ginislene Dias, Thalyne Aparecida Leite Lima, Rodrigo Mello Gomes, Egberto Gaspar de Moura, Júlio Cezar de Oliveira, Seiho (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11673749.txt.
Description
Paulo Cezar de Freitas Mathias and a large research team published a rat study in two thousand twenty-four on how a mother's poor diet shapes her pups' metabolism. Mothers fed little protein while nursing can leave lasting marks on offspring. The team focused on stress hormones and sugar control in male offspring.
Rat mothers got a low-protein or normal diet for the first two weeks of nursing. At ninety days old, the male pups faced fasting or doses of a stress-hormone-like drug. Pups of low-protein mothers barely reacted to long fasting or to the drug given into the brain. Given the drug body-wide, both groups had blood sugar swings, but the low-protein pups reacted more strongly. The findings tie early diet to lifelong sugar handling.
Catalog record
| CREATOR | Paulo Cezar de Freitas Mathias, Aline Milena Dantas Rodrigues, Patrícia Cristina Lisboa, Rosiane Aparecida Miranda, Ananda Malta, Tatiane Aparecida Ribeiro, Luiz Felipe Barella, Ginislene Dias, Thalyne Aparecida Leite Lima, Rodrigo Mello Gomes, Egberto Gaspar de Moura, Júlio Cezar de Oliveira, Seiho |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 45 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |