Lactate Is a Strong Predictor of Poor Outcomes in Patients with Severe Traumatic Brain Injury

Bharti Sharma, Winston Jiang, Yashoda Dhole, George Agriantonis, Navin D Bhatia, Zahra Shafaee, Kate Twelker, Jennifer Whittington, Bruno Meloni, Brandon Lucke-Wold · 2024

Read Lactate Is a Strong Predictor of Poor Outcomes in Patients with Severe Traumatic Brain Injury by Bharti Sharma, Winston Jiang, Yashoda Dhole, George Agriantonis, Navin D Bhatia, Zahra Shafaee, Kate Twelker, Jennifer Whittington, Bruno Meloni, Brandon Lucke-Wold (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11673745.txt.

Description

Bharti Sharma and co-authors ask whether blood lactate can predict how patients with severe traumatic brain injury will fare. Lactate builds up when cells burn sugar with too little oxygen. Their 2024 study looks back at cases treated at one top-level trauma center from 2020 through 2023. Lactate was measured when patients arrived and again when they entered the intensive care unit.

High lactate went with worse injury severity scores and worse coma scores. It also went with more days in the hospital and in the unit, more days on a ventilator, and more deaths. Lactate fell with age in this group. A slow fall in the level during the unit stay also marked a long stay. The team names lactate a strong, cheap sign that such patients face a hard course. They urge its use in early triage and in talks with families.

Catalog record

CREATORBharti Sharma, Winston Jiang, Yashoda Dhole, George Agriantonis, Navin D Bhatia, Zahra Shafaee, Kate Twelker, Jennifer Whittington, Bruno Meloni, Brandon Lucke-Wold
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE46 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11673745

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