Proteins Associated with Neurodegenerative Diseases: Link to DNA Repair
Svetlana N Khodyreva, Nadezhda S Dyrkheeva, Olga I Lavrik, Marta Lualdi · 2024
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Description
Svetlana Khodyreva and co-authors review, in a 2024 paper, how proteins tied to brain degeneration also work in DNA repair. Nerve cells suffer DNA damage readily, and failed repair can kill them. The full picture of repair inside the nervous system is still incomplete.
The review sums up two repair routes that matter most in nerve cells: one that fixes small base damage, and one that rejoins broken strands. It gathers recent data on repair proteins linked to degenerative diseases. One protein, PARP1, receives special attention for its dual roles. Turning basic repair knowledge into treatments is the field's standing challenge. This map shows where the known proteins sit in that effort.
Catalog record
| CREATOR | Svetlana N Khodyreva, Nadezhda S Dyrkheeva, Olga I Lavrik, Marta Lualdi |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 87 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |