Three-Dimensional Bioprinting for Retinal Tissue Engineering

Kevin Y. Wu, Rahma Osman, Natalie Kearn, Ananda Kalevar · 2024

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Description

Kevin Wu and co-authors (2024) review how 3D bioprinting might rebuild the retina, the eye's light-sensing lining, for people whose own is failing. The retina is a hard target: a layered sheet of cell types, threaded with blood vessels, with exact wiring between layers. Bioprinting lays down living cells in precise patterns — extrusion, droplets, or laser — building tissue layer by layer. The review walks through each printing method's strengths.

Much of the progress sits in the bioinks, the gels that carry the cells. Formulations aim to copy the retina's softness and chemistry, keep cells alive through printing, and hold shape afterward. The authors survey scaffold materials and attempts at its vascular and layered structure. Their verdict is measured: printing a working retina remains distant, but each piece, inks, cells, architecture, is advancing, and the review maps what a real attempt will require.

Catalog record

CREATORKevin Y. Wu, Rahma Osman, Natalie Kearn, Ananda Kalevar
YEAR2024
COLLECTIONPAPERS
FORMATTXT
FILE SIZE52 KB
VERSION1.0
LICENSECC BY 4.0
RIGHTSCC BY
SOURCEEurope PMC

Source: https://europepmc.org/articles/PMC11673743

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