Gold Kiwi-Derived Nanovesicles Mitigate Ultraviolet-Induced Photoaging and Enhance Osteogenic Differentiation in Bone Marrow Mesenchymal Stem Cells
Doyeon Kim, Chanho Lee, Manho Kim, Ju Hyun Park, Dimitris Kletsas, Marianna Kapetanou, Aleksandra Mladenovic · 2024
Read Gold Kiwi-Derived Nanovesicles Mitigate Ultraviolet-Induced Photoaging and Enhance Osteogenic Differentiation in Bone Marrow Mesenchymal Stem Cells by Doyeon Kim, Chanho Lee, Manho Kim, Ju Hyun Park, Dimitris Kletsas, Marianna Kapetanou, Aleksandra Mladenovic (2024) in the Tower of Babel, a free online library of public-domain works preserved in clean, searchable text. No sign-up. The full text is served as a plain-text file at a predictable URL, where text is present: https://antarctic-labs.com/tower-of-babel/pmc-11673108.txt.
Description
Doyeon Kim and co-authors tested kiwi-derived nanovesicles on aging bone stem cells, in a 2024 study. Bone marrow stem cells build bone by maturing into bone cells, but aging weakens that power. The team took tiny vesicles from gold kiwi fruit and applied them to human stem cells aged by ultraviolet light. The vesicles entered the cells without harming them.
After light exposure, treated cells carried fewer harmful oxygen byproducts. Their growth and movement, both dulled by the light, recovered well. Treated cells also returned to a healthier fate balance: more bone building, with stronger bone genes and mineral deposits, and less fat making. The authors present the vesicles as a promising material for bone diseases such as osteoporosis.
Catalog record
| CREATOR | Doyeon Kim, Chanho Lee, Manho Kim, Ju Hyun Park, Dimitris Kletsas, Marianna Kapetanou, Aleksandra Mladenovic |
|---|---|
| YEAR | 2024 |
| COLLECTION | PAPERS |
| FORMAT | TXT |
| FILE SIZE | 43 KB |
| VERSION | 1.0 |
| LICENSE | CC BY 4.0 |
| RIGHTS | CC BY |
| SOURCE | Europe PMC |